Welcome to Bosse-lab

We are a RESIST-funded group located at CSSB Hamburg and part of Hannover Medical School. We are associated with the Leibniz Institute of Virology (LIV).

Viruses assemble in a complex order of consecutive morphogenesis events. Our research aims to illuminate the spatiotemporal regulation of these morphogenesis events at the single-particle level. We use three-dimensional live-cell microscopy to quantify the kinetics and dynamics of viral macromolecular complexes in living cells at the single-particle level and create computational pipelines to analyze large image datasets. Correlative electron microscopy complements our measurements with ultrastructural data on cellular organization. Proteome-wide structural predictions of viral proteins and their interactions now enable structural systems biology of virus morphogenesis.

Have a look at our HerpesFolds database that doubles as a cheat sheet of homologs! And if you are more interested in poxviruses, check out our PoxFolds database.

More info about us can be currently found on our CSSB or LIV web pages.